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Secretors and non secretors - an important differentiation for blood group nutrition

Blood group antigens in the blood and in body secretions - blood group antigens only in the blood -- digestion according to secretor status -- immune system according to secretor status -- less blood coagulation with secretors -- secretor gens on chromosomes 11 and 19 -- secretor test according to Lewis system
by Michael Palomino (2006 / translation 2012)

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-- Dr. Peter J. D'Adamo / Catherine Whitney: 4 Blutgruppen. Vier Strategien für ein gesundes Leben. Mit Rezeptteil (Piper 2001) (orig. English: 4 Blood Types, 4 Programs. Live Right 4 Your Type)
-- Peter D'Adamo: 4 Blutgruppen - richtig leben. Das individuelle Konzept für körperliches und seelisches Wohlbefinden (Piper 2002) (orig. English: 4 Blood Types, 4 Diets. Eat Right 4 Your Type)


Blood group antigens in the blood and in the body fluids - blood group antigens only in the blood

So called "secretors" have blood group antigens in the blood AND in the body fluids respectively in the secretions. "Non secretors" have their blood group antigens ONLY in the blood. 80% of a blood group are secretors, 20% are non secretors, but about 40% approximately of the food is affected by this differentiation. That's why it's important to know the secretor status (4 Strategien, p.404). Secretor status withing the blood group is important. 80% are secretors, 20% are non secretors (richtig leben, p.213).

D'Adamo:

<Most people (between 80 and 85 per cent of the population) have blood group antigens in their body fluids. These persons are called "secretors" because they secrete their blood group antigens into body fluids as for example saliva, mucus and sperm.> (richtig leben, p.25)
(orig. German:
<Die meisten Leute (zwischen 80 und 85 Prozent der Bevölkerung) weisen zudem in den Körperflüssigkeiten frei umherschwimmende Blutgruppen-Antigene auf. Diese Personen bezeichnet man als 'Sekretoren', weil sie ihre Blutgruppen-Antigene in Körpersekrete wie beispielsweise Speichel, Schleim und Sperma absondern.> (richtig leben, S.25)

Blood group of secretors can be determined by blood AND body fluids (saliva, mucus, and sperm). Blood group of non-secretors ONLY can be determined with the blood (4 Strategien, p.404).

Dr. D'Adamo indicates:

<With secretors, blood group can be determined not only with the blood but also with the other body fluids. [...] Blood group antigens can be found in the fluids of different body zones, and therefore they also have more possibilities to proof the blood group than non-secretors. Humans which have blood group antigens only in their blood are called "non-secretors" because in the other body fluids they have no blood group antigens.> (richtig leben, p.25)
(orig. German:
"Beim Sekretor lässt sich die Blutgruppe nicht nur anhand des Blutes, sondern auch durch andere Körperflüssigkeiten bestimmen. [...] Bei Sekretoren finden sich in verschiedenen Körperregionen Blutgruppen-Antigene, und deshalb verfügen sie auch über mehr Nachweismöglichkeiten für die Blutgruppe als Non-Sekretoren. Menschen, bei denen Blutgruppen-Antigene nur im Blut, aber nicht in anderen Körperflüssigkeiten nachweisbar sind, werden als 'Non-Sekretoren' bezeichnet." (richtig leben, S.25)

The more active saliva of secretors - less holes in the teeth

D'Adamo:

<Saliva of secretors contains essentially more variety and all in all a higher share of carbohydrates than saliva of non secretors. The carbohydrate structures of the mucins in the saliva can agglutinate some mouth bacteria and some thin skin particles and plaque particles. Despite of the blood group the secretors normally get less holes in their teeth than non secretors - above all there where smooth surfaces of the teeth are affected.> (richtig leben, p.84)
(orig. German:
"Der Speichel von Sekretoren enthält eine wesentlich grössere Vielfalt und einen insgesamt höheren Anteil an Kohlenhydraten als jener von Non-Sekretoren. Die in den Mucinen des Speichels vorkommenden Kohlehydratstrukturen können einige Mundbakterien und auch Häutchen- und Plaque-Partikel zusammenballen. Ungeachtet der Blutgruppe weisen Sekretoren im Durchschnitt weniger Zahnlöcher auf als Non-Sekretoren - im besonderen dort, wo glatte Zahnoberflächen betroffen sind." (richtig leben, S.84)

Studies about the relation between secretor status and holes in their teeth are for example:

-- Arneberg, P. / Kornstad, L. / Nordbo, H. / Gjermo, P.: Less dental caries among secretors than among non-secretors of blood group substance. In: Scand J Dent Res, November 1976; 84 (6): p.362-366
-- Holbrook, W.P. / Blackwell, C.C.: Secretor status and dental caries in Iceland. In: FEMS Microbiol Immunol, June 1989; 1 (6-7): p.397-399
-- Kaslick, R. S. / West, T. L. / Chasens, A. I.: Association between AB0 blood groups, HL-A antigens and periodontal diseases in young adults: A follow-up study. In: J. Periodontol, June 1980; 51 (6): p.339-342
-- Nikawa, H. / Kotani, H. / Sadamori, S. / Hamada, T.: Denture stomatitis and AB0 blood types; In: J Prosthet Dent, September 1991; 66 (3): p.391-394
(richtig leben, p.507)

Digestion according to secretor status

Certain kinds of food can have a very different effect for secretors or non secretors. At the other side rhesus factors and status of MN system do not play hardly any role concerning compatibility of food.

D'Adamo:

<Their secretor status can have an effect if certain kinds of food are completely digested and metabolized. Therefore every list of food is rated also secretors and non secretors in separate columns. Most humans are secretors and can follow with a good feeling the column for secretors, but there can be big differences for the 20% of non secretors.> (richtig leben, p.213)
(orig. German:
<Ihr Sekretor-Status kann sich darauf auswirken, ob Sie bestimmte Nahrungsmittel voll verdauen und verstoffwechseln können. Deshalb enthält jede Nahrungsmittelliste bei der Bewertung separate Spalten für Sekretoren und Nicht-Sekretoren. Zwar sind die meisten Menschen Sekretoren und können guten Gewissens den Empfehlungen in der Spalte für die Sekretoren folgen, aber die abweichenden Empfehlungen können einen grossen Unterschied machen, wenn Sie zu den etwa 20 Prozent Nicht-Sekretoren gehören.> (richtig leben, S.213)

With blood group A for example the secretors have no problems processing carbohydrates in their blood group diet. But non secretors have problems with it (richtig leben, p.28-39), and therefore non secretors of blood group A "eventually  have to rise their protein share (for example with deep sea fish and poultry) and have to reduce the supply of carbohydrates." (richtig leben, p.29)


Antigens in body liquids are nursing the body's own bacteria

Antigens (sugar connections) in mucus serve as food for the body's own bacteria - they like this sugar. Therefore the body's own bacteria are strong enough eliminating foreign elements. For example the body's own intestine bacteria strains are converting the blood group antigens into short-chained fatty acids "which are very healthy for the colon." (richtig leben, p.175)


Immune system according to secretor status

Dr. D'Adamo indicates:

<Secretor status can have a heavy influence to the characteristics of the immune system and is connected with many diseases and metabolism troubles.> (richtig leben, p.25)
(orig. German:
"Der Sekretor-Status kann einen merklichen Einfluss auf die Merkmale des Immunsystems ausüben und ist mit einer Vielzahl von Krankheiten und Stoffwechselstörungen verknüpft." (richtig leben, S.25)

Dr. D'Adamo admits that nature with antigens in the body liquids wants to establish one more protection (richtig leben, p.26-27).

The words of Dr. D'Adamo:

<It's not clear why there are secretors and non-secretors. But it can be presumed that the secretor status has something to do with nature's will installing an additional protection shield (richtig leben, p.26) the first humans did to have. There are some indications that the non-secretor status is elder than the secretor status, and that the non secretor status was more compatible with the digestion system of the hunters and collectors.> (richtig leben, p.27)
(orig. German:
<Weshalb die einen Menschen Sekretoren sind und die anderen Non-Sekretoren, ist bislang noch nicht eindeutig geklärt. Es ist aber zu vermuten, dass der Sekretor-Status irgend etwas mit dem Bemühen der Natur zu tun hat, für einen zusätzlichen Schutzschild (richtig leben, S.26) zu sorgen, über den unsere Artgenossen er allerersten Frühzeit nicht verfügten. Manches deutet darauf hin, dass der Non-Sekretor-Status genetisch älter ist als der Sekretor-Status und mit dem Verdauungssystem der Jäger und Sammler möglicherweise verträglicher war.> (richtig leben, S.27)

Secretor status is a barrier more against "troublemakers" like
-- bacteria
-- pollutants
-- irritants (richtig leben, p.27).

With the secretors these intruders are even "attacked" in the saliva. With the non-secretors the agents can intrude into their body and are only killed by the organism itself (richtig leben, p.27).


Less blood clotting with secretors

Blood clotting with secretors is always less as with non secretors. Secretors of blood group 0 have the lowest blood clotting rate of all blood groups (richtig leben, p.28).

Diseases according to secretor status

More Basedow with non-secretors: People without antigens in their saliva (non-secretors) have a significantly higher illness rate with Basedow illness (hyperthyroidism) richtig leben, p.84).

More mucus illnesses with non-secretors: Secretors have a higher protection against germs and lectins. Lectins producing superfluous mucus can coagulate for example in the saliva with antigens and are excreted. so, secretors have less mucus diseases:
-- allergies
-- illnesses of respiratory ways
-- ear infections (richtig leben, p.85).

Secretor gens on chromosomes 11 and 19

The secretor gen can be found on the chromosomes 11 and 19 and has effect on the organism:

Dr. D'Adamo:

<At the other side of 9q34, on the chromosomes 11 and 19, are the important cousins of the blood group gen - the secretor gens. They are independent from their blood group, but the secretor gens have effect varying the blood groups.> (richtig leben, p.25)
(orig. German:
"Gegenüber von 9q34, auf den Chromosomen 11 und 19, sitzen die überaus wichtigen leiblichen Vettern des Blutgruppengens - die blutgruppenspezifischen Sekretor-Gene. Obgleich unabhängig von Ihrer Blutgruppe, beeinflusst Ihr Sekretor-Gen die Art und Weise, in der sich Ihre Blutgruppe offenbart." (richtig leben, S.25)

Secretor test according to the Lewis system

The secretor test is performed according to the Lewis system:

Lewis a+ b- are non secretors
Lewis a- b+ are secretors
Lewis a- b- are Lewis negative, 6% of the white population, 16% of the black population, they are counted to the non-secretors
Lewis a+ b+ is very rare (richtig leben, p.26).

Dr. D'Adamo:

<Secretor status can be determined fast and without any difficulty using the Lewis System, a blood group system which is connected with secretor genetics. The same gen is responsible for the secretor type and also for the Lewis System. This Lewis System can be found on chromosome 19. Two different antigens are possible there, with the names Lewis a and Lewis b [...].> (richtig leben, p.25)
(orig. German:
"Der Sekretor-Status lässt sich rasch und mühelos bestimmen, und zwar mit Hilfe des Lewis-Systems, eines Blutgruppensystems, das mit der Sekretorgenetik insofern funktionell verzahnt ist, als dasselbe Gen sowohl für den Sekretor-Typ als auch das Lewis-System zuständig ist. In dem auf Chromosom 19 angesiedelten Lewis-System können zwei mögliche Antigene zustandekommen, und zwar mit der Bezeichnung Lewis a und Lewis b [...]." (richtig leben, S.25)

<There are three groups to differentiate: Lewis a+ b- (richtig leben, p.25), Lewis a- b+ and Lewis a- b- (the fourth variation - Lewis a+ b+ - is very rare). [...]

The explanation of the connection between secretor status and Lewis System is the following: secretors are converting their Lewis a -antigens into the Lewis b -form (=Lewis b+), but non-secretors don't do that (Lewis a+ is not converted).

But this test has a little flaw. For members of the type Lewis a- b- this test is not appropriate. Their organism is not capable to form the Lewis substances, and therefore neither in their blood nor in their body fluids can be found markers of +a or +b. These persons can be secretors or non-secretors in respect of blood group substances, but concerning parts of the Lewis System they will be always non-secretors.> (richtig leben, p.26)
(orig. German:
"Der Sekretor-Status lässt sich rasch und mühelos bestimmen, und zwar mit Hilfe des Lewis-Systems, eines Blutgruppensystems, das mit der Sekretorgenetik insofern funktionell verzahnt ist, als dasselbe Gen sowohl für den Sekretor-Typ als auch das Lewis-System zuständig ist. In dem auf Chromosom 19 angesiedelten Lewis-System können zwei mögliche Antigene zustandekommen, und zwar mit der Bezeichnung Lewis a und Lewis b [...]." (richtig leben, S.25)

"Unterschieden wird nach drei Gruppen: Lewis a+ b- (richtig leben, S.25), Lewis a- b+ und Lewis a- b- (eine vierte Variante - Lewis a+ b+ - kommt äusserst selten vor). [...]

Erklären lässt sich die Verbindung zwischen Sekretor-Status und Lewis-System folgendermassen: Sekretoren wandeln ihre Lewis a -Antigene in die Lewis b -Form um (=Lewis b+), Non-Sekretoren hingegen nicht (es bleibt bei Lewis a+).

Allerdings besitzt dieser Test ein kleines Manko. Für Angehörige des Typs Lewis a- b- ist er nämlich ungeeignet. Ihr Organismus ist nicht imstande, Lewis-Substanzen zu bilden, und deshalb sind weder in ihrem Blut noch in ihren Körperflüssigkeiten +a - oder +b -Merkmale zu finden. Diese Personen können zwar, was Blutgruppen-Substanzen angeht, Sekretoren oder Non-Sekretoren sein, sind aber in puncto Lewis-Bestandteile immer Non-Sekretoren." (richtig leben, S.26)

Diseases according to secretors and non-secretors

Non-secretors are more vulnerable for immune diseases, above all for infectious diseases (richtig leben, p.131).

Dr. D'Adamo indicates:

<In general non-secretors have a much higher risk to suffer with immune diseases than secretors, especially when this illness is initiated by an infectious organism. Non-secretors have genetically difficulties to eliminate immune complexes from their tissue, so they are more vulnerable to "attacking" tissue which is surrounding them. IN other words: Non-secretors have a tendency to perceive their own tissue as an enemy.> (richtig leben, p.131)
(orig. German:
"Im Allgemeinen haben Nicht-Sekretoren ein sehr viel grösseres Risiko, an einer Immunkrankheit zu leiden als Sekretoren, und zwar besonders dann, wenn diese Krankheit durch einen ansteckenden Organismus ausgelöst wird. Nicht-Sekretoren haben genetisch bedingte Schwierigkeiten, Immunkomplexe aus ihrem Gewebe zu entfernen, was ihre Anfälligkeit gegenüber 'angreifendem' Gewebe erhöht, das sie umfasst. Mit anderen Worten: Nicht-Sekretoren neigen eher dazu, ihr eigenes Gewebe als feindselig wahrzunehmen." (richtig leben, S.131)

Diseases in connection with the immune system with higher vulnerability for non-secretors

Non-secretors suffer more diseases than secretors:
-- more inflammations
-- more diabetes (type 1 and 2)
-- with diabetes of type 1 there are more problems with yeast fungus of Candida albicans (above all in the mouth and in the upper zone of the gastrointestinal tract)
-- more fibromyalgia with all non-secretors of all blood groups (80% of the affected with fibromyalgia are non-secretors) [above all women with combined symptoms like heavy pains, bodily and psychical exhaustion, troubles with sleep, concentration and memory, and irritable colon and irritable bladder].
(from: http://www.medizin.de/gesundheit/deutsch/1810.htm)

Non-secretors suffer more immune diseases than secretors:

-- Spondylitis ankylosans

(Spondylitis ankylosans is also called Spondylarthritis ankylopoetica or ankylozizing spondylitis. An older name is Morbus Bechterew. All these names stand for an infectious disease of the bands and joints of the spine, of the rib joints and of some tendons and enthesis of peripheral joints. Also the eyes and in rare cases the inner organs can be affected. Spondylitis ankylosans is a chronic disease.
(from: http://www.medizinfo.de/rheuma/arthritis/spondylitis_ankylosans.htm)

-- reactive arthritis

(Reactive arthritis are inflammatory processes in the peripheral joints (hands and feet) and/or of the spine, in combination with general symptoms and inflammatory changes with other organs. These inflammations are coming after an infection of urine or sexual organs or after an infection of the intestine zone.
from: http://www.rheumaportal.ch/?site=interessierte&menu=rheuma&sub=entzErkrankungen&doc=spondarth&subdoc=reitsynd)

-- Arthritis psoriatica

(
Arthritis psoriatica is emerging mostly between 20 and 40 years. In many cases the affected persons are suffering psoriasis since many years already. Characteristic is that this arthritis psoriatica is attacking the final joints of the fingers, and the middle or final joints of the toes, and the knees. In well 40 percent of the cases the spine is also part of the illness. During the first stadium the illness is making itself felt by heel pains. Add to this there is often a second inflammation, the inflammation of the iris in the eye.
from: http://www.psoriasis-netz.de/psa_dhabrosch.html)

-- Sjögren's Syndrome

(Sjögren's Syndrome is an inflammation of glands of tears and saliva, and of glands of mucosal. By the inflammation the glands are damaged, and they are giving less liquid then. When the tear glands are attacked, there is less lacrimal fluid, and the conjunctiva of the eye is irritated. The eye is red then and one has the feeling having sand corns in the eyes. When saliva glands are attacked, so the quantity of saliva is reduced and the mouth is dry. Attacked saliva glands are swollen and can also provoke pains. Burning eyes and dry mouth are the most often symptoms of Sjögren's Syndrome. When mucosal glands are attacked this also can provoke dry zones, for example in the nose and in the genital zone.

Sjögren's Syndrome can limit itself on the attack of gland tissues. Then the patient "only" suffers the symptoms mentioned above. But the illness can also spread and can develop for being a general disease, with fever, fatigue, muscle pains, joint pains, eventually also with a polyarthritis - an inflammation of several joints. More complicated the illness will be when it is developing within an illness which is existing already. Mostly this is a chronic polyarthritis or a Lupus erythematodes. This form of Sjögren's Syndrome is also called "secondary" Sjögren's Syndrome.
from: http://www.rheumazentrum-heidelberg.de/Patienteninformation/Sjoegrensyndrom.htm)

-- multiple sclerosis

-- Graves disease [Morbus Basedow, with many symptoms by over or under function of thyroid gland, see http://de.wikipedia.org/wiki/Morbus_Basedow]

More illnesses with special vulnerabilities for non-secretors are

-- often repeated infections of urinary ways

-- or a "complex" disease pattern: 80% of the affected people with "complex" disease pattern are non-secretors. Diagnose is difficult, and healing processes are slowly (richtig leben, p.132).

Therefore it's important to know the secretor status with a test [and until today (Effective 2006) industry and laboratories in Europe and Asia have no such a secretor test available. One has to order it in "America", it's a catastrophe].


Inflammations of urinary ways with blood group B

Non secretors of blood group B are especially in danger for chronic inflammations of their urinary ways. The complete alimentation has to be well adapted against bacterial infections (richtig leben, p.132).

Inflammations of urinary ways with blood group A

Blood group A has got a high risk for inflammations of urinary ways. Non-secretors have a higher risk by 25% (richtig leben, p.132).


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